L-Histidine
Product Overview
CAS Number: 71-00-1
L-Histidine is an essential α-amino acid that plays a crucial role in protein synthesis and various metabolic processes. This pharmaceutical-grade amino acid is characterized by its imidazole side chain, which contributes to its unique biochemical properties.
L-Histidine is widely utilized in pharmaceutical formulations, nutritional supplements, cell culture media, and biochemical research applications due to its high purity and consistent quality specifications.
Technical Specifications
| Test Parameter | Specification | Test Method |
|---|---|---|
| Appearance | White to off-white crystals or crystalline powder | Visual observation |
| Identification | HPLC retention time corresponds to reference standard | HPLC |
| Specific Rotation [α]D²⁰ | +12.0° to +14.0° | USP <781> |
| pH (1% aqueous solution) | 7.0 - 8.5 | USP <791> |
| Chloride (Cl⁻) | ≤ 0.05% | USP <221> |
| Sulfate (SO₄²⁻) | ≤ 0.03% | USP <221> |
| Iron (Fe) | ≤ 30 ppm | USP <241> |
| Heavy Metals (as Pb) | ≤ 15 ppm | USP <231> |
| Loss on Drying | ≤ 0.20% | USP <731> |
| Residue on Ignition | ≤ 0.4% | USP <281> |
| Assay (dried basis) | ≥ 98.5% | USP <541> |
| Any Individual Impurity | ≤ 0.50% | USP <621> |
| Total Impurities | ≤ 2.0% | USP <621> |
| Total Plate Count | ≤ 1000 cfu/g | USP <61> |
| Yeast & Molds | ≤ 100 cfu/g | USP <61> |
| E. Coli | Negative | USP <62> |
| Salmonella | Negative | USP <62> |
Applications
Pharmaceutical Industry
Used in pharmaceutical formulations and as an active pharmaceutical ingredient in various therapeutic applications.
Nutritional Supplements
Essential component in dietary supplements and sports nutrition products for protein synthesis support.
Cell Culture Media
Critical amino acid component in cell culture media for biotechnology and research applications.
Feed Additives
Nutritional supplement in animal feed formulations to support growth and development.
Storage & Handling
Store in tight containers at controlled room temperature (15-30°C). Protect from moisture and direct sunlight. Handle in accordance with good manufacturing practices.
Refer to Material Safety Data Sheets (MSDS) prior to handling and processing. Follow standard safety protocols for pharmaceutical-grade amino acids.
Request Quote
For detailed specifications, pricing, and availability, please contact our sales team.
Contact Us